Albert Siryaporn

Albert Siryaporn
210C Rowland Hall
University of California, Irvine
Irvine, CA 92697
Physics & Astronomy
(949) 444-2201
Associate Professor of Physics & Astronomy
Assistant Professor of Molecular Biology and Biochemistry

Professor Siryaporn and his team explore how mechanical forces regulate bacterial pathogenesis using an approach that combines techniques from biophysics, molecular biology, genetics, fluid mechanics, and computational modeling. The group's fundamental questions are: 1. What is the role of mechanosensation in bacterial virulence, 2. How does mechanosensation affect colonization, 3. What signaling mechanisms do bacteria use to detect and transduce mechanical stimuli? The Siryaporn lab uses mechano-genetics, microscopy, force measurement, and microfluidic techniques to understand how bacteria interact with and infect host cells. In particular, they explore how bacteria detect and respond to surfaces using a unique “sense of touch”. Their multi-scale approach looks at how interactions at the single-cell level drive the complex behaviors observed in large bacterial communities such as biofilms and microbiomes.

Ph.D., University of Pennsylvania

Siryaporn's developing a treatment for COVID-19 patients that uses "decoy" cells to lure virus particles away from a patient's actual cells.